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Vacuum concentrators use centrifugal force to concentrate or evaporate multiple samples under vacuum, for further analysis. The process typically requires a chemical-resistant diaphragm vacuum pump or system with special attention to your setup.
Low volatility solvents and a high gas flow at the operating pressure shows a correct chosen vacuum level. Trapping solvent vapors using a refrigerated trap is recommended to prevent pump flooding and protect air quality.
See below our vacuum pumps suitable for vacuum concentrator applications such as DNA pelleting, oligonucleotide preparations, biochemical, organic samples or large samples.
Model 2044 DryFast®
Two-stage chemical duty diaphragm vacuum pump with ultimate vacuum pressure of 9 torr (12mbar) and flow of 35 lpm@60Hz. The rugged, low maintenance oil free pump has one PTFE head, perfluoroelastomer valves, and fluoroplastic wetted surfaces that make it suitable for ethanol and water evolved during pellet drying.
Oligoneucleotide prep and biochemical/organic sample drying times with an oil-free chemical duty diaphragm pump are equivalent to oil-sealed rotary vane pumps. A diaphragm pump with flow rate of 35 lpm and ultimate vacuum pressure to 2 torr (2.7mbar) is needed to dry samples quickly. As with an oil-sealed rotary vacuum pump, the chemical duty diaphragm vacuum pump paired with a cold trap of at least -50°C is necessary. The chemical duty diaphragm pump eliminates oil changes, frequent repairs, and oil mess. Chemical duty diaphragm vacuum pumps have the chemical resistance to handle aggressive chemicals such as TFA, HCL, formic acid, and acetic acid.
Model 2042 DryFast® Ultra
Two-stage chemical duty diaphragm vacuum pump with ultimate vacuum pressure of 2 torr (2.7 mbar) and flow of 35 lpm@60Hz. The rugged, low maintenance oil free pump has two PTFE heads, perfluoroelastomer valves, and fluoroplastic wetted surfaces that make it suitable for the aggressive chemical vapors evolved during oligoneucleotide prep and biochemical/organic sample drying.
Process large volume or sample count evaporations with ease using high capacity chemical duty pumps. Minimum flow of 65 lpm and ultimate vacuum to 2 torr (1.5 mbar) are recommended.
About Welch Vacuum
Welch is a recognized provider of vacuum pumps, systems, and fittings for industrial, life sciences, and laboratory applications. We design, manufacture, and deliver products meeting the strictest requirements for mission-critical applications, and provide a comprehensive offering of products and great engineering capabilities to fit our customers’ needs.
As a reliable and trusted partner for OEMs, we stand up to the challenge of supplying best-in-class products and solutions on time to manufacturers of equipment in the life sciences, healthcare, and industrial segments.
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